Our Scanning Electron Microscope
My husband Andrew, has spent much of his life working with scanning electron microscopes (SEMs). He first learnt how to use an SEM when he was with The Wellcome Foundation doing analytical biochemistry. A few years later he went to The Wellcome Foot & Mouth Disease Virus Laboratories working on the virus as a senior technician for nearly 10 years . He also worked on feline leukaemia and equine flu amongst other things and was one of the first to produce peptides for foot and mouth disease. He has become very knowledgeable in the field of chemistry, laboratory techniques, scanning and transmission electron microscopy, biology and botany. You can see some of his work at here.
Being particularly au fait with foot and mouth disease, he also knows much about vaccines, peptides and other techniques and sometimes he amazes me with his wealth of knowledge in these areas. For those who want to know what a peptide is, it’s a string of amino acids joined together. There are 20 naturally occurring amino acids. This enables custom ‘designing’ of small fragments of protein (proteins are made of amino acids). These tailor made peptides can then be used in many ways including experimentation and vaccines for example.
I’m always grilling him and picking his brains for his thoughts on what I’m blogging about and as much of my posts are to do with nutrient minerals, particular Magnesium (Mg), his chemistry knowledge is a boon. When I first started on my Mg quest, Andrew didn’t say much. He is really quite a scientist. He will not believe anything until it has been proven beyond a reasonable doubt.
I’m a new woman
I had been taking it for a few weeks and feeling really well. I had my first good nights sleep since I can’t remember when and my muscle spasms were all but gone. Constipation was a thing of the past and I can’t remember the last time I had a migraine. My mood was upbeat and my depression had melted away. I was a new woman and the only thing I changed was to take a Mg supplement.
So when I started my crusade with Mg, I was really surprised when Andrew started taking it too. He would always avoid taking any drugs or supplements and I surmised that he could see a real change in me and so thought it was worth a try. But it wasn’t really that at all. One day I asked him why he decided to start taking Magnesium (Mg) and he said it was because of his brothers and his inevitable glaucoma (according to his optician).
The health of Andrew’s brothers
Andrew has three brothers and all three of them have their health problems. One brother has had a serious blood pressure problem for donkey’s years and also suffered a stroke. He now has been diagnosed with Type 2 diabetes and other problems. His eldest brother has had a quadruple by-pass, a stroke and recently been operated on to clear his seriously blocked carotid arteries. His third brother has been diagnosed with an enlarged liver and told to stop drinking. He actually never drinks!
Glaucoma threat
As for the glaucoma, Andrew’s father and grandfather both went blind. Because it is in the family, he has had free glaucoma tests since he was 40 years old. His first test at age 40 showed a high reading of 18mm of mercury. Once your reading reaches 21mm of mercury, you are classed as having glaucoma and need treatment for the rest of your life. For the last 15 years his test has come back as 20mm of mercury which is very worrying, another mm and he will officially have glaucoma. In 2014 his test showed 20mm again. In June 2015 after being on Mg for 3 months, his test showed a drop of 2mm down to 18mm. To me, this was very exciting. Andrew was pleased with the result but cautious. The optician didn’t think it was significant and reiterated that Andrew would inevitably get glaucoma. Andrew is due for another test this coming June and I’m hoping the result will show another drop. If so, I think it can safely be said that Mg is the reason why. There are actually a couple of research papers advocating that Mg could be a possible treatment for glaucoma.¹ ²
Out of the 4 brothers, Andrew is definitely the healthiest. He says he wants to stay that way and taking Mg will help avoid a stroke amongst other things. He has a real fear of having a stroke, being incapacitated and having to be cared for. He also said that Mg is a mineral that is necessary and vital for all life and is always used in cultures when growing up animal or plant cells. My ears pricked up and I asked him what ratio of Mg was used in cultures in relation to Ca. He said he didn’t actually know but would find out for me.
Meanwhile, Andrew says he will continue taking Mg probably for life as he knows its vital importance, especially as research has shown that it helps keep the arteries clear of calcification.
Calcification!
Now calcification is something that is a real worry for everyone, especially in these modern times with our maladjusted diet and nutrient depletions and I will be doing another post on this serious subject in a week or so.
I have now been doing this website since August 2015 and the biggest problem I have found is trying to convince people to take this mineral and to cut down on the ‘star’ mineral Calcium (Ca). Ca of course is necessary, as necessary as Mg but we have gone overboard as have the food manufacturers, the supplement producers, Big Pharma and their PPIs (proton pump inhibitors) and antacids like ‘Tums’.
Excess Calcium = Magnesium Deficiency
This is the nub of Mg deficiency today. We are all taking in too much Ca and not enough Mg and this simple fact needs to be disseminated to the whole population. Andrew knows this fact but I didn’t realize and nor did he, that his knowledge actually held the proof that an equal ratio of Mg to Ca will generate healthy cells.
Cultures are made up in the laboratory to produce healthy cells in vitro. As it happens, we already know what the ratio should be to keep cells healthy. Laboratory technicians and researchers are doing this all the time. The cultures they use to produce healthy cells will always have Mg in them. They will also have Ca, but what ratio do they use for these cultures?
Culture Recipes
The culture media recipe is worked out to produce, within a petri dish (known as in vitro), healthy cells with which to do experiments and other biological tasks. It is obvious that for an experiment to be successful, you first have to start with the healthiest cells you can culture. For your information I give below the part of a recipe from two well known culture media showing the Mg and Ca within that recipe. Those who work in a laboratory environment will probably know about these already but perhaps don’t realize the significance of the ratio of Mg to Ca. Don’t worry about the jargon, just know Andrew has worked out the elemental amounts for each of the two minerals Mg and Ca as follows:
- McCoy’s Tissue Culture Medium Recipe:
MgSO4 (anhydrous) – Elemental Magnesium is 20mg per litre of distilled water.
CaCl2 – Elemental Calcium is 18mg per litre of distilled water.
Ratio of Magnesium to Calcium equals – 10:9
- Ham’s Tissue Culture Medium for Mammalian Cells:
MgSO4.7H2O – Elemental Magnesium is 15mg per litre of distilled water.
CaCl2 – Elemental Calcium is 16mg per litre of distilled water
Ratio of Magnesium to Calcium equals 15:16
An equal balance is best
Notice both of the ratios for each of these recipes are approximately 1:1. This is the ratio that nutritionalists and naturopaths are advocating to be the optimum for cell health and many are saying it should be more Mg to Ca
Why are they doing it to us?
For this to be the standard within a laboratory or research environment for producing healthy cells, what are we doing consuming amounts of Ca that can be anything up to 10 times the amount of Mg, causing by default, a severe Mg deficiency in many of us.
- Why are we not being educated by the medical profession on the importance of this vital balance?
- Why are the food manufacturers fortifying our foods with Ca?
- Why are we being encouraged to supplement with massive amounts of Ca especially for women and the older generation?
- Why are we being coaxed into taking massive amounts of Ca Carbonate (chalk) in antacids such as ‘Tums’?
- Why is the medical fraternity advocating that everyone with osteoporosis and arthritis take extra Ca?
- Why do the majority of Ca supplements have none, or very little, Mg in them to balance?
Prevention is better than cure
Remember this, you have trillions of cells within your body. Having healthy cells in a petri dish is no different than having healthy cells in the human body. Excess Ca is causing all kinds of health problems for us. It’s about time the medical profession came clean and started looking at preventative measures with natural vitamins, minerals and other nutrients and keeping us in good health. This is the better strategy rather than waiting for us to get sick then controlling our sickness for life with poisonous drugs and various unpleasant surgeries and therapies. A doctor without knowledge of nutrition is like a firefighter without knowledge of water!
I welcome any comments you have about this subject and if you or a loved one have been blighted by a calcification type of disease like osteoporosis, arthritis, atherosclerosis, kidney stones or have experience or think you may have Mg deficiency, I would be very interested to hear about it. Ches
- The Role of Magnesium in the Pathogenesis and Treatment of Glaucoma. Feyzahan Ekici et al Hindawi Publishing Corp. Volume 2014, Article ID 745439, http://dx.doi.org/10.1155/2014/745439
- Identification of hydroxyapatite spherules provides new insight into subretinal pigment epithelial deposit formation in the aging eye. Richard B Thompson et al, Edited by Jeremy Nathans, Johns Hopkins University, Baltimore, MD, http://www.pnas.org/content/112/5/1565.full
What Magnesium supplement do you recommend?
Hi there June, please take a look at my article – what is Magnesium Chloride. You can even make your own up from food quality Mg Chloride crystals, which is much cheaper than buying the equivalent such as ReMag.
My dad went into hospital feeling terrible and could not walk of stand. They said he was having to much calcium due to taking Aricept. With dialysis. They stopped the Aricept but he still cannot think, walk, understand and does not know what, where, or why. Please is this forever? THE DOCTOR SAID NO STROKE. but he is so confused. Days and nights are reversed. He is freezing.
Hello Dr Rhonda, I am sorry to hear about your dad, is he still in hospital? Too much Ca could probably be applied to a good part of the general population, so what is your dad suffering from. Is it Alzheimer’s, if so, how long has he been diagnosed with it. You speak of dialysis, has your dad got kidney disease? I would definitely recommend a supplement of Mg (not oxide) but not if he is on dialysis. However, there is another Mg supplement he could take (liposomal), but you would need to consult a doctor who is au fait with nutrition (ND) as well as being an MD. Has he had kidney stones? Has he had a coronary calcium scan? Is he underweight? There are so many questions. If you could elaborate and give me all his symptoms and tell me what he has been officially diagnosed with, perhaps I could point you in the right direction.
Hi Ches,
The title of your post pricked up my ears! Although I love to learn something new everyday, I also like to enhance my knowledge of things I am already aware of. Your post is fantastic and went into great details to help everyone at whatever level of knowledge they are at.
Personally, I don’t do very well with pills, so I use magnesium topically and have seen incredible results in my life. I became aware of calcification in 2009, when I went through health challenges and ‘obsessed’ with research and study. I avoid manufactured calcium like a plague and I am glad your post identified this. Great research.
Thank goodness Chuka there are people out there that know the importance of the balance of these two important minerals, I find it very gratifying. Thank you also for your kind comments. Yes, topical use is really great but many people can’t be bothered with it and prefer to use oral supplements which take less time to administer. Your awareness of calcification is a life saver and through your own research you will have the best chance possible to live a long and healthy life. I hope you try to spread the word to others. It is quite difficult to pursuade people about something they have not heard from the the medical profession! Good health to you and yours always. Ches
Hi Chess, I learned so much from your post!
I had no idea the calcium and magnesium levels should be equal, I’m one of those many people that kind of neglected magnesium and always thought Calcium to be much more important. But this will change from now.
Do you think that someone could experience these side effects while taking calcium supplements? Assuming he/she doesn’t have a high calcium deficiency, just taking calcium supplements because it’s said to be “healthy”
Hi Ashley and thanks for reading the post. It is very rare for people to have a calcium deficiency, there’s just too much calcium out there for us to consume, sometimes without our knowledge. Beware that if you continually ingest large amounts of calcium and ignore your intake of magnesium, you will become magnesium deficient by default. Magnesium is vital to regulate the calcium you have in your body. Not enough magnesium means that calcium will migrate to parts of the body where is should not be. Simply put, magnesum makes sure that calcium goes to your bones and teeth and also ensures that the calcium that is necessary in the blood is always kept dissolved. Without magnesium to dissolve calcium in the blood, calcium will start to calcify around the body. This is particularly dangerous if too much calcium migrates to the arteries and cardiovascular system. Remember also that calcium is the tensor in the muscles and magnesium is the relaxer. Calcium without magnesium will cause muscle aches and spasms, constrict arteries and cause blood pressure, constrict the bronchials and exacerbate asthma, excite nerves and cause anxiety, panic attacks and depression. Unless magnesium is available within each of our trillions of cells, calcium, which should reside outside of our cells, will be allowed in and cause untold damage. Ches
Fabulous explanation! Thank you!
Thank you for your kind words June. You may be interested in this article on calcification, it’s in 2 parts.
This is an excellent article!
You have definitely done a lot of research for this website and it shows!
I am not a big lover of milk or dairy products so I take a calcium supplement which contains magnesium and boron also.
A teaspoon contains calcium 800mcg and magnesium 350mcg do you think this is the correct ratio ?
Hi Maureen and thanks for your kind comments. Are you sure you’re taking mcg and not mg? Anyway, a ratio where calcium is higher than magnesium ie 800:350 in your case, is biased towards calcium which is not ideal. Try and go for a 1 to 1 ration calcium to magnesium. I take 600mg of magnesium chloride each day and just 1 pint of milk gives me my RDA amount of calcium of 600mg. But other food I eat will up my calcium to be more than my magnesium so I make sure I consume magnesium rich foods as well. Ches
Too much of anything can be bad. Calcium included, I am not too sure if this is a common issue but I am now educated on it after coming across your site. I think it is very important to keep a very balanced diet to avoid the issues that come with too much or too little of certain nutrients
Hi there Blake and thanks for your comments. Unfortunately, the problem lies with the lack of knowledge by doctors and the public about the magnesium to calcium balance. Be sure, it is a vital issue and most people today will have some sort of calcification within their bodies because of the excess we consume. Magnesium is not mentioned as being the necessary regulator of calcium. Without magnesium, calcium will migrate to places in your body where it should never be. As Dr Seelig said, “most modern heart disease is caused by magnesium deficiency”. If you consume too much calcium in relation to magnesium, you will be magnesium deficient by default! Ches
Sorry to hear about your husband’s and his relatives’ health issues. I have heard a lot of products are fortified with Calcium but I have never had any idea you should also take Magnesium in an equal ratio to prevent it from being blocked by your body. Thanks for the informative article!
Thanks for your kind comments Matthew. Yes, take heed when eating your cereals, orange juice or other popular foods. Check out the calcium content and make sure you have equal magnesium. Some magnesium rich foods like almonds for instance, have an equal quantity of magnesium and calcium in them. That’s fine, almonds are good, but just make sure you’re not overdosing on calcium. There is much more calcium in our foods nowadays than magnesium and supplementation is necessary to keep your levels of magnesium as near equal to calcium as possible. Good health to you, Ches
Fascinating subject which you appear to know so much about. I am currently building my first site called karateforseniors, aimed at older people taking up the martial arts. Would magnesium supplements help older people to keep active? If so I could link my site to yours and also, maybe get you to write a guest post?
Hi Stewart and thanks for reading the post. Yes, Magnesium would be of great benefit for seniors especially as we get more deficient as we get older if we fail to do something about it! As for writing a guest post, I’ll think on that one. It takes me quite a while to research each post. At the moment I can just about cope with one a week! Ches